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Gerard Rosse

Dart NeuroScience, San Diego, CA

Title: Advances and Applications of Supercritical Fluid Chromatohgraphy in Drug Discovery

Biography

Biography: Gerard Rosse

Abstract

Innovative technologies to make better compounds and make them faster have been implemented. The presentation will focus on the design of a highly automated facility with a multistep process for the rapid analysis and purification of small molecules using Supercritical Fluid Chromatography-Mass Spectrometry (SFC-MS). The recent introduction of a new generation of SFC-MS instruments is revolutionizing the field of chromatography. The instrumentation and the robotic infrastructure to support the production of ~10,000 compounds/month will be discussed. Finally the benefits of an enhanced SFC-MS technology platform to increase productivity and decrease costs will be discussed.