Vlad Orlovsky
SIELC Technologies, USA
Title: Evolution of mixed-mode from “mixing†silica gels to core-shell mixed-mode technology
Biography
Biography: Vlad Orlovsky
Abstract
In recent years, mixed-mode chromatography emerged as a powerful separation technique with alternative selectivity. Evolution of this technology covering old “mixing” approach and single ligand design is being discussed with the emphasis on selectivity benefits and critical applications. Comparison of single, dual, tri-modal columns are offered and evaluated. The first line of core-shell mixed-mode stationary phases is presented. Numerous examples in pharmaceutical, environmental, food and agricultural sciences are presented.